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Sunday, October 11, 2009

Creating Bone from Stem Cells

Posted by Prahallad Panda on 9:31 PM Comments

"The Scholar's Lion" at :w:Columbia ...Image via Wikipedia
Stem cells are cell in primary stage, without a command for differentiation in one line i.e. bone , skin, muscle and other tissue. They can be given command in special set up to grow in one line. Previously blood vessels has been developed and now bone. But a vascularised bone and other attached tissue like cartilage requires further effort. But I think we are in the right direction.
clipped from
Scientists have created part of the jaw joint in the lab using human adult stem cells.
New bone created in the lab
They say it is the first time a complex, anatomically-sized bone has been accurately created in this way.
It is hoped the technique could be used not only to treat disorders of the specific joint, but more widely to correct problems with other bones too.
The Columbia University study appears in Proceedings of the National Academy of Sciences.
The bone which has been created in the lab is known as the temporomandibular joint (TMJ).
Problems with the joint can be the result of birth defects, arthritis or injury.
Although they are widespread, treatment can be difficult.
The joint has a complex structure which makes it difficult to repair by using grafts from bones elsewhere in the body.
The latest study used human stem cells taken from bone marrow.
These were seeded into a tissue scaffold, formed into the precise shape of the human jaw bone by using digital images from a patient.

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