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Monday, October 12, 2009

Scalp, Nail Psoriasis Improve with TNF Inhibitor

Posted by Prahallad Panda on 7:40 PM Comments

Psoriasis of the back.Psoriasis of Back.
Psoriasis is a very bad skin disease and treatment is not that satisfactory. The clipped article highlights the role of tumor necrosis factor in its treatment.
I quote;
"The scalp severity score declined by more than 80% and the nail index by 36% after 16 weeks of treatment with the TNF inhibitor adalimumab (Humira) with or without concomitant topical treatment. "

Psoriasis of a fingernailPsoriasis of nail.
clipped from www.medpagetoday.com

By Charles Bankhead, Staff Writer, MedPage Today
Published: October 09, 2009
Reviewed by Dina M. Began, MD; Assistant Professor, Department of Medicine (Dermatology), Albert Einstein College of Medicine and
Dorothy Caputo, MA, RN, BC-ADM, CDE, Nurse Planner

Action Points

  • Explain to patients that a biological drug improved psoriasis of the skin and scalp, as well as skin lesions.
  • Explain that the drug is not approved in the U.S. for treatment of psoriasis.
  • Note that this study was published as an abstract and presented at a conference. These data and conclusions should be considered preliminary until published in a peer-reviewed journal.
Scalp and nail involvement slowed the overall skin response to anti-TNF therapy but did significantly affect improvement rates at the end of the study, investigators reported here at the European Academy of Dermatology and Venereology meeting.

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