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Friday, July 30, 2010

Synthesis of Natural Joint

Posted by Prahallad Panda on 7:24 AM Comments

Bone was made outside the body, so also flesh. Now it is joint. If, it finally comes to the clinicians, it will be a boon.

A natural replacement for worn-out joint


PARIS: Scientists have shown for the
first time that it may be possible to replace a human hip or knee with a joint
grown naturally inside the body using the patient's stem cells.

In
experiments on rabbits, the researchers coaxed the animals' stem cells to
rebuild the bone and cartilage of a missing leg joint, according to a study
published on Thursday. "This is the first time an entire joint surface was
regenerated with return of functions including weight-bearing and locomotion,"
lead researcher Jeremy Mao, a professor at Columbia University Medical Center,
said.

In the
experiments, Mao and colleagues removed the forelimb thigh joint of 10 rabbits,
and then implanted a kind of scaffolding made of biologically compatible
materials.

The
fact that the regenerated limb joint was created from the stem cells in the host
animal — rather than being harvested and then cultivated outside the body
— is also unprecedented, they said.
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